According to latest researchers from University Of Eastern Finland Pigments in Berries called anthocyanins increases SIRT6( Sirtuin 6) enzyme which reduce the expression of Cancer genes and Cancer Cells growth.
Sirtuins regulates the expression of genes that controls the function of cells through key cellular signalling pathways.
If function of sirtuins changes by ageing or any reason its causes various disease.
So if we regulate this enzymes we can treated Cancer better.
Research found cyanidin in wild bilberry, blackcurrant and lingonberry, a anthocyanins which increases SIRT6 enzyme levels in human colorectal cancer cell and decrease the expression of Twist1 and GLUT1 cancer genes and at the same time it's increases the expression of the tumour suppressor FOXO 3 genes in cells.
Scientists tried for developing a new drugs that regulate SIRT6 function.
Scientists also developed a computer based model to predict how different flavonoids compound in plants I can regulate the SIRT6 enzyme.
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